Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior.

@article{Basset1994Stromelysin3IS,
  title={Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior.},
  author={Paul Basset and C B Wolf and Nicolas Rouyer and J. P. Bellocq and M. C. Rio and Pierre Chambon},
  journal={Cancer},
  year={1994},
  volume={74 3 Suppl},
  pages={1045-9}
}
BACKGROUND It has long been proposed that secreted proteinases, including the matrix metalloproteinases, play an important part in tumor progression in mediating extracellular matrix remodeling. More recently, it has been suggested that extracellular proteinases also regulate growth factors and cytokines that may contribute to tumor progression. METHODS RNA in situ hybridization and immunohistochemistry were used to study the expression, in breast and other types of human carcinomas, of the… CONTINUE READING