Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases

@article{Rajput2007StromalMC,
  title={Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases},
  author={Ashish B. Rajput and Dmitry Turbin and Maggie C U Cheang and David K. Voduc and Sam Leung and KarenA. Gelmon and Cyril Blake Gilks and David G. Huntsman},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={107},
  pages={249 - 257}
}
We have previously demonstrated in a pilot study of 348 invasive breast cancers that mast cell (MC) infiltrates within primary breast cancers are associated with a good prognosis. Our aim was to verify this finding in a larger cohort of invasive breast cancer patients and examine the relationship between the presence of MCs and other clinical and pathological features. Clinically annotated tissue microarrays (TMAs) containing 4,444 cases were constructed and stained with c-Kit (CD-117) using… CONTINUE READING
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