Stromal derived growth factor-1 (CXCL12) modulates synaptic transmission to immature neurons during post-ischemic cerebral repair

@article{Ardelt2013StromalDG,
  title={Stromal derived growth factor-1 (CXCL12) modulates synaptic transmission to immature neurons during post-ischemic cerebral repair},
  author={Agnieszka A. Ardelt and Bula J. Bhattacharyya and Abdelhak A. Belmadani and Dongun Ren and Richard J. Miller},
  journal={Experimental Neurology},
  year={2013},
  volume={248},
  pages={246-253}
}
In response to ischemic injury, the brain mounts a repair process involving the development of new neurons, oligodendrocytes, and astrocytes. However, the manner in which new neurons integrate into existing brain circuitry is not well understood. Here we observed that during the four weeks after transient middle cerebral artery occlusion (MCAO), doublecortin (DCX)-expressing neural progenitors originating in the subventricular zone (SVZ) were present in the ischemic lesion borderzone, where… CONTINUE READING
Highly Cited
This paper has 20 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

Poststroke neurogenesis: emerging principles of migration and localization of immature neurons.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry • 2008
View 4 Excerpts
Highly Influenced

The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2008
View 8 Excerpts
Highly Influenced

Heart disease and stroke statistics—2012 update: a report from the American Heart Association

T. N. Turan, S. S. Virani, N. D. Wong, D. Woo, M. B. Turner
Circulation 125, • 2010

Gene profiles and electrophysiology of doublecortin-expressing cells in the subventricular zone after ischemic stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2009
View 1 Excerpt