Stromal-derived factor 1 signalling regulates radial and tangential migration in the developing cerebral cortex.

@article{Liapi2008StromalderivedF1,
  title={Stromal-derived factor 1 signalling regulates radial and tangential migration in the developing cerebral cortex.},
  author={Anastasia Liapi and James Pritchett and Owen T. Jones and Nobutaka Fujii and John G. Parnavelas and Bagirathy Nadarajah},
  journal={Developmental neuroscience},
  year={2008},
  volume={30 1-3},
  pages={
          117-31
        }
}
Stromal-derived factor 1 (SDF-1), a known chemoattractant, and its receptor CXCR4 are widely expressed in the developing and adult cerebral cortex. Recent studies have highlighted potential roles for SDF-1 during early cortical development. In view of the current findings, our histological analysis has revealed a distinct pattern of SDF-1 expression in the developing cerebral cortex at a time when cell proliferation and migration are at peak. To determine the role of chemokine signalling during… CONTINUE READING
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