Stromal cell independent growth of bipotent B cell--macrophage precursors from murine fetal liver.

Abstract

We have established stromal cell independent culture conditions under which single murine hematopoietic progenitor cells give rise to B lymphocytes and macrophages. IL-11, mast cell growth factor, and IL-7 are sufficient for the growth of B lineage cells from AA4.1+B220-Mac-1-Ly6A+ fetal liver cells isolated at day 12 of gestation. These conditions are also… (More)

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@article{Kee1994StromalCI, title={Stromal cell independent growth of bipotent B cell--macrophage precursors from murine fetal liver.}, author={Barbara L Kee and Ana Cumano and Norman N. Iscove and Ciara Paige}, journal={International immunology}, year={1994}, volume={6 3}, pages={401-7} }