Stromal biomarkers in breast cancer development and progression

@article{Rudnick2012StromalBI,
  title={Stromal biomarkers in breast cancer development and progression},
  author={Jenny A. Rudnick and Charlotte Kuperwasser},
  journal={Clinical & Experimental Metastasis},
  year={2012},
  volume={29},
  pages={663-672}
}
Breast cancer is a heterogeneous, multi-factorial disease of aberrant breast development whose etiology relies upon several microenvironmental changes within the tissue. Within the last decade, it has become widely accepted that tumor cells frequently rely on signals from an activated microenvironment in order to proliferate and survive within a tissue. This activated tissue microenvironment involves the appearance of αSMA + fibroblasts (referred to as “cancer associated fibroblasts”), the… CONTINUE READING
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