Stromal Expression of MicroRNA-21 in Advanced Colorectal Cancer Patients with Distant Metastases

Abstract

BACKGROUND The aim of this study was to determine the regional heterogeneity and clinicopathological significance of microRNA-21 (miR-21) in advanced colorectal cancer (CRC) patients with distant metastasis. METHODS miR-21 expression was investigated by using locked nucleic acid- fluorescence in situ hybridization in the center and periphery of the… (More)
DOI: 10.4132/jptm.2016.03.19

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