Stroke location and brain function in an embolic rabbit stroke model.

@article{Brown2010StrokeLA,
  title={Stroke location and brain function in an embolic rabbit stroke model.},
  author={Aliza Brown and Robert D. Skinner and Ren{\'e} Cort{\'e}s Flores and Leah Hennings and Michael J. Borrelli and John D Lowery and William C. Culp},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={2010},
  volume={21 6},
  pages={903-9}
}
PURPOSE Current rabbit stroke models often depend on symptoms as endpoints for embolization and produce wide variation in location, size, and severity of strokes. In a further refinement of an angiographic embolic stroke model, localized infarctions were correlated to neurologic deficits with the goal to create a rabbit model for long-term studies of therapies after stroke. MATERIALS AND METHODS New Zealand White rabbits (4-5 kg; N = 71) had selective internal carotid artery (ICA) angiography… CONTINUE READING

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