author={Geoffrey Alan Donnan and Marc Fisher and Malcolm Robert Macleod and Stephen M. Davis},
  journal={The Lancet},
Should ateplase be used before endovascular thrombectomy in patients with acute stroke?
It is still controversial whether to use alteplase intravenous thrombolysis before EVT in patients with acute ischemic stroke within 4.5 h of onset, as many epidemiological studies have shown that patients have no significant benefit from bridging endovascular thrombectomy compared with direct EVT (dEVT).
Prevention and follow-up in thromboembolic ischemic stroke: Do we need to think out of the box?
A comparative study of medication use after stroke in four countries
Management of acute ischemic stroke, thrombolysis rate, and predictors of clinical outcome
Thrombolysis and mechanical thrombectomy rate was higher than that of previous reports, and higher NIHSS proved an independent predictor of unfavorable clinical outcome and death.
Cerebral ischemic stroke and different approaches for treatment of stroke
This compilation furnishes conventional and recent treatments of stroke along with their hurdles like the gap between preclinical and clinical studies, and suggests effective routes of administration of drugs for the treatment of brain ischemia specifically nose-to-brain route and effectiveness of different dosage forms precisely nanoformulations, as the most effective dosage form.
Extended Risk Factors for Stroke Prevention.
Iron Pathophysiology in Stroke.
Recent research progress in iron pathophysiology following cerebral stroke is discussed, focusing molecular regulation of iron metabolism and potential treatment targets.
Stroke in Parkinson's disease.
  • Y.F. Huang, C. Yeh, C. Liao
  • Medicine, Psychology
    QJM : monthly journal of the Association of Physicians
  • 2019
PD increases stroke risk and influences post-stroke outcomes, and patients' characteristics and medical conditions from claims data of Taiwan's National Health Insurance are collected.
Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice
The aim of this narrative review is to explore the pathophysiology of brain-lung interactions after acute ischaemic stroke and the management of mechanical ventilation in these patients.


Blood-brain barrier experiments with clinical magnetic resonance imaging and an immunohistochemical study.
Evaluated brain magnetic resonance (MR) images of the rat obtained using a 1.5T MR machine in several blood-brain barrier (BBB) experiments revealed typical findings of acute cerebral infarction and showed vasogenic edema and contrast enhancement, representing vascular damage.