author={G. Donnan and M. Fisher and M. Macleod and S. Davis},
  journal={The Lancet},
Stroke is the second most common cause of death and major cause of disability worldwide. Because of the ageing population, the burden will increase greatly during the next 20 years, especially in developing countries. Advances have occurred in the prevention and treatment of stroke during the past decade. For patients with acute stroke, management in a stroke care unit, intravenous tissue plasminogen activator within 3 h or aspirin within 48 h of stroke onset, and decompressive surgery for… Expand
72 Citations

Paper Mentions

Interventional Clinical Trial
This is a placebo controlled, randomized, double blinded study including Phase 1 and Phase 2. Phase I study is a safety assessment and Phase 2 study is incline to assess effectiveness of… Expand
ConditionsAcute Stroke, Cerebral Infarction, Infarction, Anterior Cerebral Artery, (+2 more)
InterventionBiological, Other
Interventional Clinical Trial
One of the disabling consequences of stroke is hemipleic shoulder pain. Hemiplegic shoulder pain could be most important hinderance to upper extremity function after stroke . Evidence… Expand
InterventionBiological, Other
Interventional Clinical Trial
There is good evidence of the effectiveness of regular physical activity in the primary and secondary prevention of stroke. STARFISH is a smartphone-based application designed as a… Expand
Prevention and follow-up in thromboembolic ischemic stroke: Do we need to think out of the box?
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A comparative study of medication use after stroke in four countries
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  • Highly Influenced
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Multiparametric prediction of acute ischemic stroke tissue outcome using CT perfusion datasets
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The association between rural residence and stroke care and outcomes
  • 33
Progression of vasogenic edema induced by activated microglia under permanent middle cerebral artery occlusion.
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Lessons from Metabonomics on the Neurobiology of Stroke
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