Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. II. Structure determination.

@article{Fredenhagen1990StrobilurinsFG,
  title={Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. II. Structure determination.},
  author={Andreas Fredenhagen and Paul Hug and Heinrich Peter},
  journal={The Journal of antibiotics},
  year={1990},
  volume={43 6},
  pages={
          661-7
        }
}
The structures of the new antibiotics strobilurins F, G and H and of compound 8 were determined by spectroscopic methods, mainly 1H and 13C NMR and confirmed by degradation reactions. 
Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. I. Fermentation, isolation and biological activity.
Three new strobilurins F, G and H, antibiotics with antifungal activity, were isolated from cultures of Bolinea lutea Sacc. These new compounds differ from previously described analogs in their
Investigations into the biosynthesis of the antifungal strobilurins† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8ob00608c
Prestrobilurin A, formed via benzoate and cinnamate, has been identified as the first enzyme free intermediate in strobilurin biosynthesis.
Bolineol, a novel co-metabolite of strobilurins A, F and G from Bolinea lutea
TLDR
A mycelial co-metabolite of strobilurin A, F and G from Bolinea lutea, which is named bolineol, has been characterised for the first time and its structure has been deduced from its spectral characteristics and those of its acetate.
The antifungal strobilurins and their possible ecological role
TLDR
The strobilurins and the closely related oudemansins are new respiration inhibitors, binding to the Qp centre of cytochrome b, and appear to play a role in securing nutrient resources for the producers from competing fungi.
Feeding of L-phenylalanine as precursor enhances strobilurin A biosynthesis in the basidiomycte, Strobilurus tenacellus
TLDR
The hypothesis that L-phenylalanine is the putative precursor of strobilurin A and during biosynthesis probably, the aromatic part of the compound is derived from this precursor is supported.
Review of strobilurin fungicide chemicals
  • H. Balba
  • Biology, Chemistry
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
  • 2007
TLDR
This class of fungicides is relatively new, as crop protection products and information about them is still fairly scarce, but syntheses and chemistry of natural and synthetic strobilurins are discussed.
Non-β-Lactam Antibiotics
TLDR
Some classes of fungal metabolites which are presently used as medicinal, veterinary or agricultural antibiotics, as well as some newer candidates for development are reviewed.
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References

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Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. I. Fermentation, isolation and biological activity.
Three new strobilurins F, G and H, antibiotics with antifungal activity, were isolated from cultures of Bolinea lutea Sacc. These new compounds differ from previously described analogs in their
ANTIBIOTICS FROM BASIDIOMYCETES. XVIII
TLDR
Two new antifungal (E)-β-methoxyacrylates, strobilurin C and oudemansin B, were isolated from cultures of Xerula longipes and Xerula melanotricha and elucidated by spectroscopic methods.
Antibiotics from basidiomycetes. XVIII. Strobilurin C and oudemansin B, two new antifungal metabolites from Xerula species (Agaricales).
TLDR
Two new antifungal (E)-beta-methoxyacrylates, strobilurin C and oudemansin B, were isolated from cultures of Xerula longipes and Xerula melanotricha and elucidated by spectroscopic methods.
Antibiotics from basidiomycetes. XXXII. Strobilurin E: a new cytostatic and antifungal (E)-beta-methoxyacrylate antibiotic from Crepidotus fulvotomentosus Peck.
TLDR
Strobilurin E is a novel antibiotic of the (E)-beta-methoxyacrylate (MOA) class produced by mycelial cultures of the agaric Crepidotus fulvotomentosus that exhibits very high cytostatic activities which are accompanied by reversible morphological alterations of the cells.
The strobilurins--new antifungal antibiotics from the basidiomycete Strobilurus tenacellus.
TLDR
The strobilurins are two antifungal antibiotics which were isolated from the mycelium of Strobilurus tenacellus strain No. 21602 and strongly inhibited the incorporation of radioactive leucine, uridine, and thymidine into the acid-insoluble fraction of cells.
Antibiotika aus Basidiomyceten, III. Strobilurin A und B, antifungische Stoffwechselprodukte aus Strobilurus tenacellus
Die Konstitutionsaufklarung der Strobilurine A und B (4 bzw. 5) wird beschrieben. Es handelt sich um 1-Arylhexatriene, die eine endstandige β-Methoxyacrylat-Gruppierung enthalten. Antibiotics
Characterisation of binding of the methoxyacrylate inhibitors to mitochondrial cytochrome c reductase.
TLDR
Results have direct implications for the proper use of MOA inhibitors in experiments designed to analyse the structure/mechanism relationship in cytochrome c reductase and point mutations recently described in MOA-inhibitor-resistant mutants can no longer be taken to affect necessarily the ubihydroquinone binding site.
Antibiotika aus Basidiomyceten, 28. Hydroxystrobilurin D, ein antifungisches Antibiotikum aus Kulturen von Mycena sanguinolenta (Agaricales)
Aus Kulturen des Blatterpilzes Mycena sanguinolenta wird das antifungische Hydroxystrobilurin D (3) isoliert. Seine Strukturaufklarung beruht auf spektroskopischen Untersuchungen sowie auf der
, ein antifungisches Antibiotikum ai ^ Kulturen von Mycena sanguinolenta ( agaricales )
  • Liebigs Ann . Chem .
  • 1988
Hydroxystrobilurin D, ein antifungisches Antibiotikum ai^ Kulturen von Mycena sanguinolenta (agaricales)
  • Liebigs Ann. Chem
  • 1988
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