Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease.

@article{Tanganelli2004StriatalPA,
  title={Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease.},
  author={Sergio Tanganelli and K Sandager Nielsen and Luca Ferraro and Tiziana Antonelli and Jan Kehr and Rafael Franco and Sergi Ferr{\'e} and Luigi Francesco Agnati and Kjell Fuxe and Jorgen Scheel-Kr{\"u}ger},
  journal={Parkinsonism & related disorders},
  year={2004},
  volume={10 5},
  pages={273-80}
}
Behavioral and microdialysis studies have been performed on antagonistic A(2A)/D(2) interactions in animal models of Parkinson's Disease. The behavioral analysis involved studies on locomotor activity in reserpinized mice, haloperidol-induced catalepsy in rats and rotational behavior in rats with unilateral 6-OHDA lesions of the ascending DA pathways (Ungerstedt model). Dual probe microdialysis studies were indirectly performed on the striatopallidal GABA neurons by studying extracellular… CONTINUE READING

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