Striatal infarction in the rat causes a transient reduction of tyrosine hydroxylase immunoreactivity in the ipsilateral substantia nigra.

@article{Soriano1997StriatalII,
  title={Striatal infarction in the rat causes a transient reduction of tyrosine hydroxylase immunoreactivity in the ipsilateral substantia nigra.},
  author={Michelle A. Soriano and Carles Justicia and Isidro Ferrer and Eduard Rodr{\'i}guez-Farr{\'e} and Anna M Planas},
  journal={Neurobiology of disease},
  year={1997},
  volume={4 5},
  pages={376-85}
}
Dopaminergic neurons of the substantia nigra pars compacta were examined in the rat brain following striatal infarction subsequent to transient focal cerebral ischemia. Rats had the middle cerebral artery occluded for 2 h or were sham-operated, and tyrosine hydroxylase immunoreactivity was evaluated by Western blot and immunohistochemistry at different times ranging from 1 to 60 days after ischemia. The number of tyrosine hydroxylase-immunoreactive cells in the substantia nigra pars compacta… CONTINUE READING