Striatal dopamine transporter binding in early to moderately advanced Parkinson's disease: monitoring of disease progression over 2 years.

@article{Choukr2001StriatalDT,
  title={Striatal dopamine transporter binding in early to moderately advanced Parkinson's disease: monitoring of disease progression over 2 years.},
  author={Martina Chouk{\`e}r and Klaus Tatsch and Rainer Linke and Oliver Pogarell and Klaus Hahn and Johannes Schwarz},
  journal={Nuclear medicine communications},
  year={2001},
  volume={22 6},
  pages={721-5}
}
Imaging of striatal dopamine transporter binding allows differentiation between patients with Parkinson's disease and controls. We investigated the use of this technique to monitor disease progression. We used N-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane (IPT) and single photon emission computed tomography (SPECT) to determine dopamine transporter function in eight patients with Parkinson's disease Hoehn and Yahr stage I to III over time. Patients were recruited from… CONTINUE READING