Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity

@inproceedings{Clark2012StriatalDD,
  title={Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity},
  author={Luke Clark and Paul R. A. Stokes and Kit Wu and Rosanna Michalczuk and Aaf Benecke and Ben J. Watson and Alice Egerton and Paola Piccini and David J. Nutt and Henrietta Bowden-Jones and Anne Lingford-Hughes},
  booktitle={NeuroImage},
  year={2012}
}
Pathological gambling (PG) is a behavioural addiction associated with elevated impulsivity and suspected dopamine dysregulation. Reduced striatal dopamine D(2)/D(3) receptor availability has been reported in drug addiction, and may constitute a premorbid vulnerability marker for addictive disorders. The aim of the present study was to assess striatal dopamine D(2)/D(3) receptor availability in PG, and its association with trait impulsivity. Males with PG (n=9) and male healthy controls (n=9… CONTINUE READING
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