Striatal circuits, habits, and implications for obsessive-compulsive disorder.

@article{Burguire2015StriatalCH,
  title={Striatal circuits, habits, and implications for obsessive-compulsive disorder.},
  author={Eric Burgui{\`e}re and Patr{\'i}cia Monteiro and Luc Mallet and Guoping Feng and Ann M. Graybiel},
  journal={Current opinion in neurobiology},
  year={2015},
  volume={30},
  pages={59-65}
}
Increasing evidence implicates abnormalities in corticostriatal circuits in the pathophysiology of obsessive-compulsive disorder (OCD) and OC-spectrum disorders. Parallels between the emergence of repetitive, compulsive behaviors and the acquisition of automated behaviors suggest that the expression of compulsions could in part involve loss of control of such habitual behaviors. The view that striatal circuit dysfunction is involved in OC-spectrum disorders is strengthened by imaging and other… CONTINUE READING