Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide.

@article{AbiDargham2004StriatalAD,
  title={Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide.},
  author={Anissa Abi-Dargham and Lawrence S. Kegeles and Yolanda Zea-Ponce and Osama Mawlawi and Diana Martinez and Vivian Mitropoulou and Karen O'Flynn and Harold W. Koenigsberg and Ronald L van Heertum and Thomas Cooper and Marc Laruelle and Larry J. Siever},
  journal={Biological psychiatry},
  year={2004},
  volume={55 10},
  pages={1001-6}
}
BACKGROUND Previous imaging studies demonstrated that schizophrenia is associated with increased amphetamine-induced dopamine (DA) release in the striatum, most pronounced during episodes of illness exacerbation. Schizotypal personality disorder (SPD) is a schizophrenia spectrum disorder, genetically related to schizophrenia. The goal of this study was to… CONTINUE READING