Striatal 6 * Nicotinic Acetylcholine Receptors : Potential Targets for Parkinson ’ s Disease Therapy

@inproceedings{Quik2006Striatal6,
  title={Striatal 6 * Nicotinic Acetylcholine Receptors : Potential Targets for Parkinson ’ s Disease Therapy},
  author={Maryka Quik and John McIntosh},
  year={2006}
}
The presence of distinct nicotinic acetylcholine receptor (nAChR) subtypes in specific central nervous system (CNS) areas offers the possibility of developing targeted therapies for diseases involving the affected brain region. Parkinson’s disease is a neurodegenerative movement disorder characterized by a progressive degeneration of the nigrostriatal system. 6containing nAChRs (designated 6* nAChRs) have a relatively selective localization to the nigrostriatal pathway and a limited number of… CONTINUE READING