Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction

@article{Kirber2005StretchactivatedIC,
  title={Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction},
  author={M. Kirber and J. Walsh and J. Singer},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2005},
  volume={412},
  pages={339-345}
}
  • M. Kirber, J. Walsh, J. Singer
  • Published 2005
  • Chemistry, Medicine
  • Pflügers Archiv - European Journal of Physiology
  • As in many smooth muscle tissue preparations, single smooth muscle cells freshly dissociated from the stomach of the toadBufo marinus contract when stretched. Stretch-activated channels have been identified in these cells using patch-clamp techniques. In both cell-attached and excised inside-out patches, the probability of the channel being open (Po) increases when the membrane is stretched by applying negative pressure to the extracellular surface through the patch pipette. The increase inPo… CONTINUE READING
    191 Citations
    Characterization of stretch-activated cation current in coronary smooth muscle cells.
    • X. Wu, M. Davis
    • Medicine, Biology
    • American journal of physiology. Heart and circulatory physiology
    • 2001
    • 82
    • Highly Influenced
    • PDF
    Stretch-inactivated cationic channels in single smooth muscle cells
    • 11
    Stretch-induced increases in intracellular calcium of isolated vascular smooth muscle cells.
    • 128
    Characterization of the Stretch-activated Chloride Channel in Isolated Human Atrial Myocytes
    • 36
    Stretch-activated conductances in smooth muscles.
    • 2
    Stretch-activated channels in airway epithelial cells.
    • 28
    A calcium-permeable stretch-activated cation channel in renal proximal tubule.
    • 96
    Whole cell current and membrane potential regulation by a human smooth muscle mechanosensitive calcium channel.
    • 35
    • PDF
    Stretch-induced Calcium Release in Smooth Muscle
    • 94
    • PDF

    References

    SHOWING 1-10 OF 58 REFERENCES
    Stretch-activated potassium channels in renal proximal tubule.
    • H. Sackin
    • Chemistry, Medicine
    • The American journal of physiology
    • 1987
    • 81
    Acetylcholine increases voltage-activated Ca2+ current in freshly dissociated smooth muscle cells.
    • 75
    • PDF
    Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?
    • 702
    Calcium action potentials in single freshly isolated smooth muscle cells.
    • 64
    A cation channel in frog lens epithelia responsive to pressure and calcium
    • 50
    Passive properties of the membrane of single freshly isolated smooth muscle cells.
    • 45
    Mechanotransducer ion channels in chick skeletal muscle: the effects of extracellular pH.
    • 105
    Stretch-activated cation channels in human fibroblasts.
    • 95
    Mediation of cell volume regulation by Ca2+ influx through stretch-activated channels
    • 402