Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction

@article{Kirber1988StretchactivatedIC,
  title={Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction},
  author={Michael T. Kirber and John V. Walsh and Joshua A. Singer},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={1988},
  volume={412},
  pages={339-345}
}
As in many smooth muscle tissue preparations, single smooth muscle cells freshly dissociated from the stomach of the toadBufo marinus contract when stretched. Stretch-activated channels have been identified in these cells using patch-clamp techniques. In both cell-attached and excised inside-out patches, the probability of the channel being open (P o) increases when the membrane is stretched by applying negative pressure to the extracellular surface through the patch pipette. The increase inP o… CONTINUE READING
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References

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Possible role of ion channels in stretch-induced contraction of smooth muscle

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A stretch - activated anion channel in cultured tobacco cells

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