Stretch-activated channels in single early distal tubule cells of the frog.

@article{Hurst1990StretchactivatedCI,
  title={Stretch-activated channels in single early distal tubule cells of the frog.},
  author={Annette M. Hurst and Malcolm Hunter},
  journal={The Journal of physiology},
  year={1990},
  volume={430},
  pages={13-24}
}
1. Single stretch-activated channels have been studied in cell-attached and excised patches from single early distal tubule (diluting segment) cells of Rana temporaria. 2. The channels can be reversibly activated, in both cell-attached and excised patches, by the application of negative pressure to the pipette causing mechanical stretching of the cell membrane. In cell-attached patches, application of 14.8 cmH2O negative pressure to the patch pipette increased reversibly the open probably from… CONTINUE READING