Stretch-activated cation channel in human umbilical vein endothelium in normal pregnancy and in preeclampsia.

@article{Khler1998StretchactivatedCC,
  title={Stretch-activated cation channel in human umbilical vein endothelium in normal pregnancy and in preeclampsia.},
  author={Ralf K{\"o}hler and Gilbert Sch{\"o}nfelder and Hartmut Hopp and Armin Distler and Joachim Hoyer},
  journal={Journal of hypertension},
  year={1998},
  volume={16 8},
  pages={1149-56}
}
OBJECTIVE To determine whether stretch-activated cation channels (SAC) are present in intact human umbilical vein endothelium (HUVE) and in an endothelial cell line (EA.hy) and whether they act as endothelial mechanosensors, and to determine whether endothelial SAC in HUVE from women with pregnancies complicated by preeclampsia undergo functional changes… CONTINUE READING