Stressor controllability and learned helplessness: The roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor

@article{Maier2005StressorCA,
  title={Stressor controllability and learned helplessness: The roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor},
  author={Steven F. Maier and Linda R. Watkins},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2005},
  volume={29},
  pages={829-841}
}
  • S. Maier, L. Watkins
  • Published 2005
  • Psychology, Medicine
  • Neuroscience & Biobehavioral Reviews
The term 'learned helplessness' refers to a constellation of behavioral changes that follow exposure to stressors that are not controllable by means of behavioral responses, but that fail to occur if the stressor is controllable. This paper discusses the nature of learned helplessness, as well as the role of the dorsal raphe nucleus, serotonin, and corticotropin-releasing hormone in mediating the behavioral effects of uncontrollable stressors. Recent research indicates that (a) uncontrollable… Expand
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Uncontrollable stressors produce behavioral changes that do not occur if the organism can exercise behavioral control over the stressor. Previous studies suggest that the behavioral consequences ofExpand
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The major brain serotonin (5-HT) system, the dorsal raphe nucleus (DRN)-5- HT system is discussed as a point of convergence that links these processes and how the stress-related neuropeptide, corticotropin-releasing factor (CRF) directs this by a bimodal regulation of DRN neuronal activity. Expand
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