Stressful Presentations: Mild Cold Stress in Laboratory Mice Influences Phenotype of Dendritic Cells in Naïve and Tumor-Bearing Mice

@inproceedings{Kokolus2014StressfulPM,
  title={Stressful Presentations: Mild Cold Stress in Laboratory Mice Influences Phenotype of Dendritic Cells in Na{\"i}ve and Tumor-Bearing Mice},
  author={Kathleen M Kokolus and Haley M. Spangler and Benjamin J. Povinelli and Matthew R. Farren and Kelvin P. Lee and Elizabeth A. Repasky},
  booktitle={Front. Immunol.},
  year={2014}
}
The ability of dendritic cells (DCs) to stimulate and regulate T cells is critical to effective anti-tumor immunity. Therefore, it is important to fully recognize any inherent factors which may influence DC function under experimental conditions, especially in laboratory mice since they are used so heavily to model immune responses. The goals of this report are to 1) briefly summarize previous work revealing how DCs respond to various forms of physiological stress and 2) to present new data… CONTINUE READING

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