Stress system dysregulation in pediatric generalized anxiety disorder associated with comorbid depression.

Abstract

Because chronic stress is an important risk factor for anxiety states and depressive disorders, we studied hypothalamus-pituitary-adrenal (HPA) axis and sympathetic system activity via changes in cortisol and alpha amylase activity levels in pediatric generalized anxiety disorder (GAD) patients (n = 26) with comorbid depression and a healthy comparison… (More)
DOI: 10.1002/smi.2736

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