Stress resistance in long-lived mouse models.

@article{Murakami2006StressRI,
  title={Stress resistance in long-lived mouse models.},
  author={Shin Murakami},
  journal={Experimental gerontology},
  year={2006},
  volume={41 10},
  pages={1014-9}
}
Cellular stress resistance has been observed in a variety of long-lived mouse systems. The Ames and Snell dwarf mice show altered hormonal profiles (low levels of growth hormone/IGF-1 and of other hormones). These altered hormonal profiles lead to physiological changes in cells, leading to increased resistance to multiple forms of stress including UV light, oxidative stress, heat, and the heavy metal cadmium. The cells also show resistance to carcinogen and senescence-like growth arrest induced… CONTINUE READING
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