Stress regulation of sulfotransferases in male rat liver.

  title={Stress regulation of sulfotransferases in male rat liver.},
  author={Smarajit Maiti and Shannon P. Grant and Sharon M Baker and Subramanya Karanth and Carey Pope and Guangping Chen},
  journal={Biochemical and biophysical research communications},
  volume={323 1},
Sulfotransferase (SULT) catalyzed sulfation is responsible for hormone regulation and xenobiotic detoxification. Induction of SULTs by various hormones has been reported. Stress regulation of SULTs has not been reported, however. Here we report that rat liver SULTs can be regulated by physical stress (forced running, EX) and chemical stress (the organophosphorus pesticide parathion, PS). Both EX and PS increased rat liver phenol-sulfating SULT1A1 and hydroxysteroid-sulfating SULT2A1 activities… CONTINUE READING

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