Stress-induced reduction in the rat mixed lymphocyte reaction is due to macrophages and not to changes in T cell phenotypes.

@article{Fleshner1995StressinducedRI,
  title={Stress-induced reduction in the rat mixed lymphocyte reaction is due to macrophages and not to changes in T cell phenotypes.},
  author={Monika Fleshner and Donald Bellgrau and Linda R. Watkins and Mark L Laudenslager and Steven F. Maier},
  journal={Journal of neuroimmunology},
  year={1995},
  volume={56 1},
  pages={45-52}
}
Exposure to aversive events or stressors modulates various aspects of immune function. We have previously reported that exposure to an acute stressor, inescapable tail shock (IS), resulted in a shift in T cell subpopulations in rat mesenteric lymph nodes but not in cervical lymph nodes (Fleshner et al. (1992) J. Neuroimmunol. 41, 131-142). The mesenteric CD4+/CD8+ ratio was increased immediately after exposure to IS and was due primarily to an increase in the percent of CD4+ cells. The present… CONTINUE READING

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