Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy.

@article{Radogna2018StressinducedCR,
  title={Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy.},
  author={Flavia Radogna and Marc F Diederich},
  journal={Biochemical pharmacology},
  year={2018},
  volume={153},
  pages={
          12-23
        }
}
Cancer is evading the host's defense mechanisms leading to avoidance of immune destruction. During tumor progression, immune-evading cancer cells arise due to selective pressure from the hypoxic and nutrient-deprived microenvironment. Thus, therapies aiming at re-establishing immune destruction of pathological cells constitute innovating anti-cancer strategies. Accumulating evidence suggests that selected conventional chemotherapeutic drugs increase the immunogenicity of stressed and dying… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 109 REFERENCES

P

A. D. Garg, D. V. Krysko, +9 authors J. Golab
  • de Witte, P. Vandenabeele, P. Agostinis, A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death, EMBO J 31(5)
  • 2012
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

F

M. Michaud, I. Martins, +13 authors F. Ghiringhelli
  • di Virgilio, L. Zitvogel, G. Kroemer, Autophagy-dependent 29 anticancer immune responses induced by chemotherapeutic agents in mice, Science 334(6062)
  • 2011
VIEW 19 EXCERPTS
HIGHLY INFLUENTIAL

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