Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation

Abstract

Stress insults intensify fear memory; however, the mechanism(s) facilitating this physiological response is still unclear. Here, we report the molecular, neurophysiological and behavioral findings attributing much of this effect to alternative splicing of the acetylcholinesterase (AChE) gene in hippocampal neurons. As a case study, we explored… (More)
DOI: 10.1038/sj.mp.4001446

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