Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis

@inproceedings{Razzoli2016StressinducedAO,
  title={Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis},
  author={Maria Razzoli and Andrea Frontini and Allison M. Gurney and Eleonora Mondini and Cankut Cubuk and Liora S. Katz and Cheryl Cero and Patrick J. Bolan and Joaqu{\'i}n Dopazo and Antonio Vidal-Puig and Saverio Cinti and Alessandro Bartolomucci},
  booktitle={Molecular metabolism},
  year={2016}
}
BACKGROUND Stress-associated conditions such as psychoemotional reactivity and depression have been paradoxically linked to either weight gain or weight loss. This bi-directional effect of stress is not understood at the functional level. Here we tested the hypothesis that pre-stress level of adaptive thermogenesis and brown adipose tissue (BAT) functions explain the vulnerability or resilience to stress-induced obesity. METHODS We used wt and triple β1,β2,β3-Adrenergic Receptors knockout… CONTINUE READING
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