Stress failure plays a major role in the development of high-altitude pulmonary oedema in rats.

@article{Bai2010StressFP,
  title={Stress failure plays a major role in the development of high-altitude pulmonary oedema in rats.},
  author={Chunxue Bai and Jun She and Arnaud Goolaerts and Yuanlin Song and C Shen and Jian-zhong Shen and Qun-ying Hong},
  journal={The European respiratory journal},
  year={2010},
  volume={35 3},
  pages={584-91}
}
Hypoxia and exertion are considered as the two main factors in the development of high-altitude pulmonary oedema (HAPE), however its pathophysiology remains unclear. Therefore, we established a model in which 32 Sprague-Dawley rats were randomly assigned to normoxic rest, hypoxic rest, normoxic exercise and hypoxic exercise. An altitude of 4,700 m was… CONTINUE READING