Stress during development: Impact on neuroplasticity and relevance to psychopathology

@article{Fumagalli2007StressDD,
  title={Stress during development: Impact on neuroplasticity and relevance to psychopathology},
  author={F. Fumagalli and R. Molteni and G. Racagni and M. Riva},
  journal={Progress in Neurobiology},
  year={2007},
  volume={81},
  pages={197-217}
}
Development represents a critical moment for shaping adult behavior and may set the stage to disease vulnerability later in life. There is now compelling evidence that stressful experiences during gestation or early in life can lead to enhanced susceptibility for mental illness. In this paper we review the data from experimental studies aimed at investigating behavioral, hormonal, functional and molecular consequences of exposure to stressful events during prenatal or early postnatal life that… Expand
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Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development.
  • T. Roth, J. Sweatt
  • Psychology, Medicine
  • Journal of child psychology and psychiatry, and allied disciplines
  • 2011
TLDR
Experiments in rodents continue to show that experiences during sensitive periods of development influence DNA methylation patterns of several genes, representing stable epigenetic modifications that alter gene transcription throughout the lifespan and promote specific behavioral outcomes. Expand
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