Stress during development: Impact on neuroplasticity and relevance to psychopathology

@article{Fumagalli2007StressDD,
  title={Stress during development: Impact on neuroplasticity and relevance to psychopathology},
  author={Fabio Fumagalli and Raffaella Molteni and Giorgio Racagni and Marco Andrea Riva},
  journal={Progress in Neurobiology},
  year={2007},
  volume={81},
  pages={197-217}
}
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210 Citations
Highly Influential Citations
7
Background Citations
83
Methods Citations
7
Results Citations
3

210 Citations

Prenatal Stress and Neurodevelopmental Plasticity: Relevance to Psychopathology.
TLDR
The major focus of the present chapter is to update and discuss data on behavioural, functional and morphological effects of prenatal stress in rats that may have counterparts in prospective and/or retrospective studies of gestational stress in humans.
Long-term effects of early life stress exposure: Role of epigenetic mechanisms.
Delayed BDNF alterations in the prefrontal cortex of rats exposed to prenatal stress: Preventive effect of lurasidone treatment during adolescence
Transcriptional Signatures of Cognitive Impairment in Rat Exposed to Prenatal Stress
TLDR
It is found that exposure to prenatal stress produces a significant disruption in the novel object recognition test both in male and female adult rats, although such impairment was more pronounced in females, which further support the evidence that early-life stress exposure prompts cognitive impairment.
Effects of prenatal stress on developmental anatomy of the brain and adult behavioural pathology
TLDR
The aim of this review is to examine the impacts of prenatal stress on developmental anatomy of the brain, particularly focusing on the relevant emotional and behavioural outcomes within the context of current data obtained from experimental animals.
Effects of prenatal stress on developmental anatomy of the brain and adult behavioural pathology
TLDR
The aim of this review is to examine the impacts of prenatal stress on developmental anatomy of the brain, particularly focusing on the relevant emotional and behavioural outcomes within the context of current data obtained from experimental animals.
Prenatal stress induced chromatin remodeling and risk of psychopathology in adulthood.
Long-term effects of stress early in life on microRNA-30a and its network: Preventive effects of lurasidone and potential implications for depression vulnerability
The Effects of Early Life Stress on the Brain and Behaviour: Insights From Zebrafish Models
TLDR
The zebrafish represents a novel ELS model, with the potential to contribute to answering several key questions, including a comprehensive overview of brain regions and molecular pathways that are altered by ELS and how ELS-induced molecular changes ultimately lead to behavioural changes in adulthood.
Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development.
  • T. Roth, J. Sweatt
  • Psychology, Biology
    Journal of child psychology and psychiatry, and allied disciplines
  • 2011
TLDR
Experiments in rodents continue to show that experiences during sensitive periods of development influence DNA methylation patterns of several genes, representing stable epigenetic modifications that alter gene transcription throughout the lifespan and promote specific behavioral outcomes.
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References

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Effects of early adverse experiences on brain structure and function: clinical implications
Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia
The effects of an early stressful life event on sensorimotor gating in adult rats
Long-term behavioral and neuroendocrine adaptations to adverse early experience.
Importance of Studying the Contributions of Early Adverse Experience to Neurobiological Findings in Depression
TLDR
The burgeoning evidence concerning a pre-eminent role of early adverse experience in the pathogenesis of depression is summarized and classification of depression based on developmental and neurobiological features will likely considerably improve future research in the field of depression.
Postnatal Stimulation of the Pups Counteracts Prenatal Stress-Induced Deficits in Hippocampal Neurogenesis
Prenatal stress and neonatal rat brain development
Alterations of neuroplasticity in depression: the hippocampus and beyond
Corticostriatal brain‐derived neurotrophic factor dysregulation in adult rats following prenatal stress
TLDR
The main finding is that BDNF expression is reduced in the prefrontal cortex and striatum of prenatally stressed rats, implying that adverse life events during gestation may interfere with the expression and function of this neurotrophin at adulthood in a region‐specific manner.
Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile Rhesus monkeys
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