Stress differentially regulates the effects of voluntary exercise on cell proliferation in the dentate gyrus of mice.

@article{Kannangara2009StressDR,
  title={Stress differentially regulates the effects of voluntary exercise on cell proliferation in the dentate gyrus of mice.},
  author={Timal S. Kannangara and Alina J. Webber and Joana Gil-Mohapel and Brian R Christie},
  journal={Hippocampus},
  year={2009},
  volume={19 10},
  pages={889-97}
}
It has been well-established that cell proliferation and neurogenesis in the adult mouse dentate gyrus (DG) can be regulated by voluntary exercise. Recent evidence has suggested that the effects of voluntary exercise can in turn be influenced by environmental factors that regulate the amount of stress an animal is exposed to. In this study, we use bromodeoxyuridine and proliferating cell nuclear antigen immunohistochemistry to show that voluntary exercise produces a significant increase in cell… CONTINUE READING

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