Stress controls the mechanics of collagen networks.

@article{Licup2015StressCT,
  title={Stress controls the mechanics of collagen networks.},
  author={Albert James Licup and Stefan Muenster and Abhinav Sharma and Michael Sheinman and Louise M. Jawerth and Ben Fabry and David A. Weitz and Fred C MacKintosh},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2015},
  volume={112 31},
  pages={9573-8}
}
Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has long been known that collagenous tissues exhibit a highly nonlinear stress-strain relationship, although the origins of this nonlinearity remain unknown. Here, we show that the nonlinear stiffening of reconstituted type I collagen networks is controlled by the applied stress and that the network stiffness becomes surprisingly insensitive to… CONTINUE READING

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Modeling semiflexible polymer networks

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