Stress controllability influences the ataxic properties of both ethanol and midazolam in the rat.

@article{Drugan1996StressCI,
  title={Stress controllability influences the ataxic properties of both ethanol and midazolam in the rat.},
  author={Robert C. Drugan and Tara S Coyle and Daniel J. Healy and Shan-bin Chen},
  journal={Behavioral neuroscience},
  year={1996},
  volume={110 2},
  pages={
          360-7
        }
}
Rats were administered either 80 escapable shocks or yoked inescapable shocks, were then injected with saline or several ataxic doses of either ethanol or midazolam, and then had their motoric impairment assessed by Rotarod performance. No motoric impairment was observed following saline injection. However, inescapable shock impaired Rotarod performance in response to both ethanol and midazolam at 2 hr, but not immediately poststress. Conversely, escapable shock reduced the ataxic potency of… CONTINUE READING

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