Stress as a trigger of autoimmune disease.

  title={Stress as a trigger of autoimmune disease.},
  author={Ljudmila Stojanovich and Dragomir Marisavljevich},
  journal={Autoimmunity reviews},
  volume={7 3},
The etiology of autoimmune diseases is multifactorial: genetic, environmental, hormonal, and immunological factors are all considered important in their development. Nevertheless, the onset of at least 50% of autoimmune disorders has been attributed to "unknown trigger factors". Physical and psychological stress has been implicated in the development of autoimmune disease, since numerous animal and human studies demonstrated the effect of sundry stressors on immune function. Moreover, many… CONTINUE READING


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