Stress and glucocorticoids impair retrieval of long-term spatial memory

  title={Stress and glucocorticoids impair retrieval of long-term spatial memory},
  author={Dominique J.-F. de Quervain and Benno Roozendaal and James McGaugh},
Extensive evidence from animal and human studies indicates that stress and glucocorticoids influence cognitive function. Previous studies have focused exclusively on glucocorticoid effects on acquisition and long-term storage of newly acquired information. Here we report that stress and glucocorticoids also affect memory retrieval. We show that rats have impaired performance in a water-maze spatial task after being given footshock 30 min before retention testing but are not impaired when… CONTINUE READING
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