Stress and gastrointestinal tract. II. Stress and intestinal barrier function.

  title={Stress and gastrointestinal tract. II. Stress and intestinal barrier function.},
  author={J. S{\"o}derholm and M. Perdue},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={280 1},
  • J. Söderholm, M. Perdue
  • Published 2001
  • Biology, Medicine
  • American journal of physiology. Gastrointestinal and liver physiology
  • The influence of stress on the clinical course of a number of intestinal diseases is increasingly being recognized, but the underlying mechanisms are largely unknown. This themes article focuses on recent findings related to the effects of stress on mucosal barrier function in the small intestine and colon. Experiments using animal models demonstrate that various types of psychological and physical stress induce dysfunction of the intestinal barrier, resulting in enhanced uptake of potentially… CONTINUE READING
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