Stress and anxiety across the lifespan: structural plasticity and epigenetic regulation.

@article{Hunter2013StressAA,
  title={Stress and anxiety across the lifespan: structural plasticity and epigenetic regulation.},
  author={Richard G. Hunter and Bruce S. McEwen},
  journal={Epigenomics},
  year={2013},
  volume={5 2},
  pages={
          177-94
        }
}
The brain is the central organ of the body's response to and perception of stress. Both the juvenile and the adult brain show a significant capacity for lasting physiological, structural and behavioral plasticity as a consequence of stress exposure. The hypothesis that epigenetic mechanisms might lie behind the lasting effects of stress upon the brain has proven a fruitful one. In this review, we examine the growing literature showing that stress has a direct impact on epigenetic marks at all… CONTINUE READING

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