Stress and Plasticity in the Limbic System

  title={Stress and Plasticity in the Limbic System},
  author={Robert Morris Sapolsky},
  journal={Neurochemical Research},
  • R. Sapolsky
  • Published 1 November 2003
  • Psychology
  • Neurochemical Research
The adult nervous system is not static, but instead can change, can be reshaped by experience. Such plasticity has been demonstrated from the most reductive to the most integrated levels, and understanding the bases of this plasticity is a major challenge. It is apparent that stress can alter plasticity in the nervous system, particularly in the limbic system. This paper reviews that subject, concentrating on: a) the ability of severe and/or prolonged stress to impair hippocampal-dependent… 
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