• Corpus ID: 212552325

Stress Proteins HSP 27 and HSP 70 i Predict Survival in Non-small Cell Lung Carcinoma

  title={Stress Proteins HSP 27 and HSP 70 i Predict Survival in Non-small Cell Lung Carcinoma},
  author={Ewa Małusecka and Stefania Krzyżowska-Gruca and Jacek Gawrychowski and Anna Fiszer-Kierzkowska and Zofia Kołosza and Zdzisław Krawczyk},
Background: The expression pattern of stress (heat shock) proteins (HSPs) in cancer cells is frequently different from that observed in normal cells; most often some stress-inducible HSPs are constitutively and highly expressed. The objective of this study was to determine the prognostic significance of stress proteins HSP70i and HSP27 in non-small cell lung carcinoma (NSCLC). Materials and Methods: An immunohistochemical procedure that enables unambiguous detection of HSP70i protein was used… 

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