Stress‐directed adaptive mutations and evolution

@article{Wright2004StressdirectedAM,
  title={Stress‐directed adaptive mutations and evolution},
  author={Barbara E. Wright},
  journal={Molecular Microbiology},
  year={2004},
  volume={52}
}
  • B. Wright
  • Published 2004
  • Biology, Medicine
  • Molecular Microbiology
Comparative biochemistry demonstrates that the metabolites, complex biochemical networks, enzymes and regulatory mechanisms essential to all living cells are conserved in amazing detail throughout evolution. Thus, in order to evolve, an organism must overcome new adverse conditions without creating different but equally dangerous alterations in its ongoing successful metabolic relationship with its environment. Evidence suggests that stable long‐term acquisitive evolution results from minor… Expand
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References

SHOWING 1-10 OF 76 REFERENCES
The influence of cellular physiology on the initiation of mutational pathways in Escherichia coli populations
TLDR
Predicting all the mutations fixed in adapting populations is beyond the current understanding of evolutionary processes, but the interplay between ancestor physiology and the initiation of adaptation pathways is demonstrated and definable in bacterial populations. Expand
Molecular mechanisms of genetic adaptation to xenobiotic compounds.
TLDR
Evidence is presented that a range of genetic mechanisms, such as gene transfer, mutational drift, and genetic recombination and transposition, can accelerate the evolution of catabolic pathways in bacteria, but there is virtually no information concerning the rates at which these mechanisms are operating in bacteria living in nature and the response of such rates to the presence of potential (xenobiotic) substrates. Expand
Genome-Wide Transcriptional Profiling of theEscherichia coli Responses to Superoxide Stress and Sodium Salicylate
TLDR
The genetic responses to both environmental insults revealed several common themes, including the activation of genes coding for functions that replenish reducing potential; regulate iron transport and storage; and participate in sugar and amino acid transport, detoxification, protein modification, osmotic protection, and peptidoglycan synthesis. Expand
The generation of multiple co-existing mal-regulatory mutations through polygenic evolution in glucose-limited populations of Escherichia coli.
TLDR
The multiplicity of alleles found within malT within a population derived from a single clone suggest that the periodic selection events observed previously in such populations are not a major factor in reducing genetic diversity. Expand
Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations.
TLDR
Increased fitness was accompanied by the generation of genetic diversity and not the evolution of a single winner clone, as predicted by the periodic selection model of bacterial populations. Expand
Environmentally constrained mutation and adaptive evolution in Salmonella
TLDR
It is shown that the mutation is not 'directed' and described its genetic basis, and compelling evidence is presented in support of the hypothesis that the mutational event is constrained by signals transmitted from the external environment via changes in the activity of DNA gyrase. Expand
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness.
TLDR
Growth curves and competition tests on lineages that passed through 90 cycles of single colony isolation showed that all lineages suffered reduced fitness, and the value of mutators in cellular evolution is discussed. Expand
Hypermutation in derepressed operons of Escherichia coli K12.
TLDR
Evidence is presented that starvation for leucine in an Escherichia coli auxotroph triggers metabolic activities that specifically target the leu operon for derepression, increased rates of transcription, and mutation, and that higher rates of mutation are specifically associated with the derepressed lei operon. Expand
Redesigning metabolic routes: manipulation of TOL plasmid pathway for catabolism of alkylbenzoates.
TLDR
In the experiments described here, a catabolic pathway for alkylbenzoates specified by the TOL plasmid of Pseudomonas was restructured to produce a pathway capable of processing a new substrate, 4-ethylbenzoate, and was redesigned by recruitment of genes from mutant bacteria selected for their production of either an altered pathway operon regulator or an altered C23O that is less sensitive to metabolite inactivation. Expand
A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli
TLDR
Evidence that DNA supercoiling plays a key role in the osmotic induction of proU transcription is presented, and mutations in osmZ are highly pleiotropic, affecting expression of a variety of chromosomal genes including ompF, ompC, fimA, and the bgl operon. Expand
...
1
2
3
4
5
...