Stress, superoxide, and signal transduction.

@article{GoldschmidtClermont1999StressSA,
  title={Stress, superoxide, and signal transduction.},
  author={Pascal J. Goldschmidt-Clermont and Lucia Moldovan},
  journal={Gene expression},
  year={1999},
  volume={7 4-6},
  pages={255-60}
}
A variety of stressful events can trigger the production of free radicals by exposed cells. For years, the effect of such highly reactive radicals was expected to be damaging to cells, altering their biology irreversibly. However, many recent reports have shown that reactive oxygen species can have additional functions, and contribute to important signaling pathways to regulate key biological responses, including cell migration, mitosis, and apoptosis. With this review, we address the role of… CONTINUE READING

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