Stress, sensitive periods and maturational events in adolescent depression

  title={Stress, sensitive periods and maturational events in adolescent depression},
  author={Susan Andersen and Martin H. Teicher},
  journal={Trends in Neurosciences},
In this paper, we provide an overview of how the maturation of specific brain regions and stress exposure during windows of vulnerability initiate a series of events that render adolescents exceptionally susceptible to the development of depression. This stress-incubation/corticolimbic development cascade provides a means of understanding why depression emerges with such force and frequency in adolescence. The development of the prefrontal cortex, hippocampus, amygdala and ventral striatum is… CONTINUE READING
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