Stress, genes and the biology of suicidal behavior.

  title={Stress, genes and the biology of suicidal behavior.},
  author={Dianne Currier and J. John Mann},
  journal={The Psychiatric clinics of North America},
  volume={31 2},
Suicidal behavior is partly heritable. Studies seeking the responsible candidate genes have examined genes involved in neurotransmitter systems shown to have altered function in suicide and attempted suicide. These neurotransmitter systems include the serotonergic, noradrenergic, and dopaminergic systems and the hypothalamic-pituitary-adrenal axis. With some exceptions, most notably the serotonin transporter gene promoter polymorphism (HTTLPR), replication of candidate gene association studies… CONTINUE READING
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