Streptozotocin induction of diabetes in rats leads to increased insulin-like growth factor-II/mannose-6-phosphate receptor mRNA expression in kidney but not in lung or heart.

Abstract

Insulin and glucose are thought to act as important modulators of the expression of the IGFs, their binding proteins and their receptors. It has been postulated that changes of the IGF system after diabetes onset contribute to the development of diabetes late complications. We have measured the expression of IGF-II/M6P receptor mRNA in rat kidney, lung and… (More)

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@article{Kiess1996StreptozotocinIO, title={Streptozotocin induction of diabetes in rats leads to increased insulin-like growth factor-II/mannose-6-phosphate receptor mRNA expression in kidney but not in lung or heart.}, author={Wendy Kiess and Andreas Hoeflich and Yuying Yang and H Groenbaek and Alan Flyvbjerg}, journal={Growth regulation}, year={1996}, volume={6 2}, pages={66-72} }