Streptozotocin diabetes modifies arterial pressure and baroreflex sensitivity in rats.

  title={Streptozotocin diabetes modifies arterial pressure and baroreflex sensitivity in rats.},
  author={Chiharu Maeda and T{\^a}nia G. Fernandes and Francisco Lulhier and Maria Cl{\'a}udia Costa Irigoyen},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={28 4},
Although an increased prevalence of hypertension is associated with insulin-dependent diabetes, little is known about the effect of streptozotocin (STZ) diabetes on arterial pressure (AP) regulation in rats. Changes in AP induced by STZ, as well as associated factors in blood pressure regulation such as baroreflex sensitivity, plasma renin activity (PRA), plasma glucose and insulin levels and endothelium participation, were studied in male Wistar rats weighing 287 +/- 10 g. The same seven… CONTINUE READING
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