Corpus ID: 9353491

Streptovirudins -- new antibiotics with antiviral activity. The antiviral spectrum and inhibition of Newcastle disease virus in cell cultures.

@article{Tonew1975StreptovirudinsN,
  title={Streptovirudins -- new antibiotics with antiviral activity. The antiviral spectrum and inhibition of Newcastle disease virus in cell cultures.},
  author={E. Tonew and M. Tonew and K. Eckardt and H. Thrum and B. Gumpert},
  journal={Acta virologica},
  year={1975},
  volume={19 4},
  pages={
          311-7
        }
}
Streptovirudins are new antibiotics isolated as a mixture of several structurally related compounds from fermentations of Streptomyces griseoflavus (Krainsky) Waksman et Henrici var. thuringensis JA 10124. They possess antiviral activity against RNA and DNA viruses cultivated in chick embryo cells, namely Sindbis, fowl plague, Newcastle disease (NDV), pseudorabies, vaccinia and sheep abortion viruses. The naturally formed streptovirudin complex, in concentrations of 20-2.5 mug/ml inhibited the… Expand
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