Streptomycin hydrazone derivatives: synthesis and molecular recognition in aqueous solution.

@article{FuentesMartineza2014StreptomycinHD,
  title={Streptomycin hydrazone derivatives: synthesis and molecular recognition in aqueous solution.},
  author={Juan P Fuentes-Martineza and Diana Guti{\'e}rrez-Rodrigueza and Edgar Rogel Garcia and Karla I Rivera-Mirqueza and Felipe Medrano and Oscar Torres-{\'A}ngeles and Evelin Castillo-Vargas and Blanca E Duque Monta{\~n}o and Carolina Godoy-Alc{\'a}ntar},
  journal={Natural product communications},
  year={2014},
  volume={9 10},
  pages={1449-55}
}
Five hydrazone derivatives of streptomycin were synthetized (D0h, D1ph, D2bt, D3dctf, D4ag) and characterized by IR, 1H and 13C NMR spectroscopy, mass spectrometry and elemental analysis. Protonation constants were determined by potentiometry for all derivatives. D1ph and D2bt derivatives were investigated as receptors of dicarboxylates and adenine… CONTINUE READING