Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.

  title={Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.},
  author={Bernd T Schmeck and Ralph Gross and Phillipe Dje N'Guessan and Andreas Hocke and Sven Hammerschmidt and Tim J Mitchell and Simone Rosseau and Norbert Suttorp and Stefan Hippenstiel},
  journal={Infection and immunity},
  volume={72 9},
Streptococcus pneumoniae is the major pathogen of community-acquired pneumonia and one of the most common causes of death due to infectious diseases in industrialized countries. Lung epithelium lines the airways and constitutes the first line of innate defense against respiratory pathogens. Little is known about the molecular interaction of pneumococci with lung epithelial cells. Apoptosis of lung epithelium is involved in some bacterial lung infections. In this study different pneumococcal… CONTINUE READING
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