Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix.

@article{Attali2008StreptococcusPC,
  title={Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix.},
  author={C{\'e}cile Attali and C{\'e}cile Frolet and Claire Durmort and Julien Offant and Thierry Vernet and Anne Marie Di Guilmi},
  journal={Infection and immunity},
  year={2008},
  volume={76 2},
  pages={466-76}
}
The virulence mechanisms leading Streptococcus pneumoniae to convert from nasopharyngeal colonization to a tissue-invasive phenotype are still largely unknown. Proliferation of infection requires penetration of the extracellular matrix, which occurs by recruitment of host proteases to the bacterial cell surface. We present evidence supporting the role of choline-binding protein E (CBPE) (a member of the surface-exposed choline-binding protein family) as an important receptor for human… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

The interaction between pathogens and the host coagulation system

  • H. Sun
  • Physiology
  • 2006

Similar Papers

Loading similar papers…